Obesity following unilateral hypothalamic lesions in rats.

نویسندگان

  • J MAYER
  • R J BARRNETT
چکیده

J. Mayer R. J. ........................599........................ Evidence for Echolocation in the Rat: Mark R. Rosenzweig, D. A. Riley, D. Krech .... 600 Binding of Hydrocortisone-4-C14 and Progesterone-4-C14 to Serum Albumin, Demonstrated by Paper Electrophoresis: U. Westphal, H. E. Firschein, E. M. Pearce 601 Continuous Aseending Chromatography-New Technique: H. Fischbach and J. Levine ......................60......... .... . .. . 602 Detoxication of Drugs and Other Foreign Compounds by Liver Microsomes: B. B. Brodie et al. ......................... .......... 603 Dicentrics in Wheat: J. W. Morrison ............ 604 Non-Mendelian Segregation in a Single Tetrad of Saccharomyces Ascribed to Gene Conversion: C. C. Lindegren ... 605 Communications Structure of Diatretyne 2, an Antibiotic Polyacetylenic Nitrile from Clitocybe diatreta: M. Anchel .. .. 607 Association of Susceptibility to Poliomlyelitis with Eye and Hair

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Combination unilateral amygdaloid and ventromedial hypothalamic lesions: evidence for a feeding pathway.

Previous studies have reported hyperphagia and obesity in female rats with bilateral lesions of the most posterodorsal part of the amygdala. In rats with unilateral posterodorsal amygdaloid lesions, a dense pattern of anterograde degeneration appears in the ipsilateral ventromedial hypothalamus, but not the contralateral nucleus. In the present study, female rats with unilateral ventromedial hy...

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VENTROMEDIAL HYPOTHALAMIC NUCLEI AND FEEDING BEHAVIOR

The role of the ventromedial nuclei of the hypothalamus (VMN) in food behavior was studied in adult male rats, allocated in 3 groups: control, sham and lesioned. Electrolytic lesions were induced stereotaxically (1.2 mA, 15 sec). Results revealed a significant decrease (p<O.05) in body weight (BW) and food intake (FI) in the order of lesioned <sham <control during the fIrst week. However, ...

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Activation of nuclear factor kappa B pathway and reduction of hypothalamic oxytocin following hypothalamic lesions

BACKGROUND Hypothalamic obesity (HO) occurs in patients with tumors and lesions in the medial hypothalamic region. In this study, a hyperphagic rat model of combined medial hypothalamic lesions (CMHL) was used to test which specific inflammatory molecules are involved. METHODS In order to target specific homeostatic medial hypothalamic nuclei (arcuate, ventromedial, and dorsomedial nuclei), m...

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Sex differences in body weight gains following amygdaloid lesions in rats.

Lesions of the most posterodorsal aspects of the amygdala resulted in equal weight gains (mean = 58 g) in male and female rats during a 22-day observation period. However, the absolute weight gains in the first 5 days after lesions were greater in females (+41.4 g) than in males (+18.8 g), as were the longer-term gains relative to their respective control groups. In a second study with female r...

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عنوان ژورنال:
  • Science

دوره 121 3147  شماره 

صفحات  -

تاریخ انتشار 1955